General manager Darcy Regier announced on the first day of free agency that the Sabres have agreed to terms with unrestricted free agent defenseman Steve Montador to a two-year contract. The Sabres also signed free agent defenseman Joe DiPenta to a one-year contract on July 11. They also extended contracts with 3 other players.
On July 20 the Buffalo Sabres agreed to terms with Andrej Sekera on a multi year deal and signed Clarke MacArthur to a one-year contract.
On August 11 the Sabres signed Mike Grier to a one year contract. Grier, already having played 2 seasons with the Sabres, returned after playing the last 3 with the San Jose Sharks. At midseason, the Sabres led the Northeast division with 56 points in the standings.
On January 1, 2010 the Buffalo Sabres became the first team to win consecutive games when trailing by three or more goals since Dallas did it in January 2006 in beating Anaheim 4-3 in a shootout and Detroit 6-3. Buffalo beat the Atlanta Thrashers 4-3 in overtime. It was Buffalo's second straight win in a game it trailed 3-0, following a 4-3 victory over Pittsburgh.
On March 3, 2010, the day of the trade deadline, the Sabres made two deals. The first was with the Columbus Blue Jackets which sent them Nathan Paetsch and a second round draft pick in exchange for Raffi Torres. The Sabres second and final deal sent Clarke MacArthur to the Atlanta Thrashers for third and fourth round draft picks
